Dengue haemorrhagic fever

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چکیده

The two basic methods for establishing a laboratory diagnosis of dengue infection are detection of the virus (e.g. culture) or detection of anti-dengue antibodies (serology). Until recently, detection of the virus implied solely the recovery of the virus by culture; however, current procedures can detect dengue virus RNA and specific dengue virus antigens. Consequently, these procedures are likely to become routine as the necessary reagents and instrumentation become more widely available. An understanding of the kinetics of dengue virus replication and host responses, as well as of the collection and handling of specimens, will help clarify the strengths and weaknesses of the two laboratory methods for diagnosing dengue infection.

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تاریخ انتشار 1998